Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13343107 | 0.78 | SMN1; SMN2 (0.50) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| SCHEMBL4821906 | 0.75 | LMNA (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL6570361 | 0.74 | RAB9A (0.44) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| SCHEMBL13320414 | 0.74 | CYP1A2 (0.50) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| SCHEMBL2205706 | 0.74 | RAB9A (0.54) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| SCHEMBL7525455 | 0.74 | ALDH1A1 (0.46) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| Hydrazine SCHEMBL22011 | 0.73 | PTPRA (0.53) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| SCHEMBL9094610 | 0.73 | CYP19A1 (0.41) | SMN1; SMN2ALDH1A1KDM4EGAAHIF1A | |
| Benzene SCHEMBL11747977 | 0.73 | PTPRA (0.56) | POLBSMN1; SMN2RAB9ANPC1PTPRA | |
| SCHEMBL21298 | 0.73 | PTPRA (0.56) | POLBSMN1; SMN2RAB9ANPC1PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |