Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554627 | 0.77 | CYP11B1 (0.35) | HTR1ADRD2HTR2AALDH1A1LMNA | |
| SCHEMBL12706465 | 0.75 | DRD2 (0.48) | DRD2HTR2A | |
| SCHEMBL28760382 | 0.72 | ALDH1A1 (0.34) | HTR1ADRD2HTR2AALDH1A1LMNA | |
| SCHEMBL3899800 | 0.70 | HTR2A (0.43) | DRD2HTR2AALDH1A1LMNAKDM4E | |
| SCHEMBL1121848 | 0.69 | ALDH1A1 (0.36) | HTR1ADRD2HTR2AALDH1A1LMNA | |
| SCHEMBL8574884 | 0.69 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EUSP2MMP9 | |
| SCHEMBL5637174 | 0.68 | HTR2A (0.55) | HTR1AHTR2A | |
| SCHEMBL5038998 | 0.68 | LSS (0.40) | — | |
| SCHEMBL5043730 | 0.68 | LSS (0.42) | — | |
| SCHEMBL5637167 | 0.68 | GHSR (0.40) | ALDH1A1LMNAKDM4EUSP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |