Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | BCKDK | O14874 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760382 | 0.82 | ALDH1A1 (0.34) | GRM4ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL1121848 | 0.78 | ALDH1A1 (0.36) | GRM4ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL8558730 | 0.77 | HTR1A (0.35) | GRM4ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7435913 | 0.71 | KDM4E (0.44) | ALDH1A1POLBMAPT | |
| SCHEMBL8346968 | 0.69 | PER2 (0.35) | ALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL1121782 | 0.68 | CCNB2 (0.44) | ALDH1A1LMNAPOLBMAPTBCKDK | |
| SCHEMBL8124099 | 0.68 | BCKDK (0.45) | ALDH1A1LMNAPOLBMAPTBCKDK | |
| SCHEMBL30487367 | 0.68 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBMAPTBCKDK | |
| SCHEMBL24898412 | 0.67 | BCKDK (0.47) | ALDH1A1LMNAPOLBMAPTBCKDK | |
| SCHEMBL30211547 | 0.67 | BCKDK (0.47) | ALDH1A1LMNAPOLBMAPTBCKDK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184478-A | Thiazole derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-06-10 | — | — | CN | disclosed |
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |