Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL8561616 | 0.96 | LMNA (0.42) | LMNANPSR1HTTAOC3ALDH1A1 | |
| SCHEMBL6801469 | 0.82 | AOC3 (0.41) | LMNANPSR1HTTAOC3ALDH1A1 | |
| SCHEMBL7583086 | 0.79 | ALDH1A1 (0.43) | LMNANPSR1AOC3ALDH1A1GAA | |
| SCHEMBL6865347 | 0.76 | LMNA (0.49) | LMNANPSR1HTTAOC3ALDH1A1 | |
| SCHEMBL6935441 | 0.76 | LMNA (0.49) | LMNANPSR1HTTAOC3ALDH1A1 | |
| SCHEMBL30522142 | 0.76 | MAOA (0.48) | LMNANPSR1HTTAOC3ALDH1A1 | |
| SCHEMBL20782023 | 0.76 | APP (0.47) | LMNAAOC3ALDH1A1GAAAPEX1 | |
| SCHEMBL9520196 | 0.75 | ALDH1A1 (0.49) | LMNAAOC3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11622082 | 0.74 | MEN1 (0.46) | LMNAALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL30522132 | 0.74 | MAOA (0.46) | LMNANPSR1HTTAOC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543861-B1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIOTECH PHARM (GB) | 1998-10-14 | — | — | EP | disclosed |
| US-5276153-A | Antagonist of platelet activating factor for bronchodilation | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-01-04 | — | — | US | disclosed |
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |
| WO-1992003422-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |