Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425768 | 0.89 | TAS1R3 (0.46) | TAS1R3TAS1R1ALDH1A1HTTKDM4E | |
| SCHEMBL8862522 | 0.88 | TAS1R3 (0.49) | TAS1R3TAS1R1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8558816 | 0.88 | KMT2A (0.36) | TAS1R3TAS1R1ALDH1A1HTTKDM4E | |
| SCHEMBL8556633 | 0.84 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1HTTKDM4E | |
| SCHEMBL4428398 | 0.82 | TAS1R3 (0.46) | TAS1R3TAS1R1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8651352 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HTTKDM4EKMT2ARAB9A | |
| SCHEMBL8862570 | 0.80 | TAS1R3 (0.41) | TAS1R3TAS1R1ALDH1A1KDM4ERAB9A | |
| SCHEMBL4424507 | 0.80 | MEN1 (0.41) | TAS1R3TAS1R1ALDH1A1HTTKDM4E | |
| SCHEMBL8654749 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HTTKDM4EKMT2ARAB9A | |
| SCHEMBL6998326 | 0.79 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |