Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.45 |
| ▸ | USP1 | O94782 | 1/20 | 0.43 |
| ▸ | USP19 | O94966 | 1/20 | 0.43 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499074 | 0.84 | PTGS2 (0.62) | PTGS2PTGS1PTGDR2MAOAMAOB | |
| SCHEMBL8560092 | 0.82 | USP1 (0.57) | PTGS2PTGS1USP1USP19UCHL3 | |
| SCHEMBL8561383 | 0.82 | USP1 (0.39) | PTGS2PTGS1USP1USP19ALOX5AP | |
| SCHEMBL8560331 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1USP1USP19UCHL3 | |
| SCHEMBL9026920 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1USP1USP19UCHL3 | |
| SCHEMBL8555824 | 0.79 | PTGS2 (0.45) | PTGS2PTGS1USP1USP19UCHL3 | |
| SCHEMBL8559927 | 0.79 | PTGS2 (0.49) | PTGS2PTGS1USP1USP19UCHL3 | |
| SCHEMBL8545808 | 0.79 | USP1 (0.38) | PTGS2PTGS1USP1USP19ALOX5AP | |
| SCHEMBL8561129 | 0.79 | PTGS2 (0.44) | PTGS2PTGS1USP1USP19UCHL3 | |
| Methane SCHEMBL6308908 | 0.79 | PTGS2 (0.39) | PTGS2PTGS1USP1USP19UCHL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |