Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562316 | 0.85 | HSD11B1 (0.46) | HSD11B1PPARGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2193708 | 0.81 | ATP4A (0.54) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1895446 | 0.79 | PDE10A (0.51) | PKM | |
| SCHEMBL8566754 | 0.79 | HSD11B1 (0.44) | HSD11B1PPARGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8564199 | 0.78 | MAPT (0.51) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL9276910 | 0.78 | PPARG (0.54) | HSD11B1PPARGPKM | |
| SCHEMBL8561187 | 0.77 | KMT2A (0.42) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9076921 | 0.77 | PPARG (0.41) | HSD11B1PPARGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8561996 | 0.75 | PPARG (0.46) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8563420 | 0.75 | PPARG (0.46) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |