Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 6/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599722 | 0.87 | HTT (0.36) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8560261 | 0.85 | MAPT (0.39) | MAPK1ALDH1A1TDP1MAPTLMNA | |
| SCHEMBL8557802 | 0.81 | DNM1 (0.44) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8559161 | 0.81 | DNM1 (0.44) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8555160 | 0.80 | MAPT (0.38) | ALDH1A1TDP1MAPTCYP1A2CYP2D6 | |
| SCHEMBL8083797 | 0.79 | DNM1 (0.57) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL6762129 | 0.79 | DNM1 (0.57) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL7775007 | 0.79 | MAPT (0.42) | MEN1KMT2AMAPK1TP53KDM4E | |
| Hydrochloric Acid SCHEMBL29729671 | 0.78 | MEN1 (0.58) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL1123490 | 0.78 | MEN1 (0.58) | DNM1MEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685456-B1 | Bisquaternary ammonium derivatives of 2,2'-dimethyl-1,1'binaphtyl and process for their preparation | HOECHST AG (DE) | 1998-04-15 | — | — | EP | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |