Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557802 | 0.94 | DNM1 (0.44) | HTTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8559161 | 0.94 | DNM1 (0.44) | HTTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8555160 | 0.90 | MAPT (0.38) | ALDH1A1TDP1MAPTCYP1A2CYP2D6 | |
| SCHEMBL8559212 | 0.87 | DNM1 (0.46) | HTTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8553919 | 0.83 | MAPT (0.40) | ALDH1A1TDP1MAPTCYP1A2CYP2D6 | |
| Tetrabuthylammonium SCHEMBL28415681 | 0.76 | KCNH2 (0.42) | HTTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16671703 | 0.76 | TLR8 (0.45) | HTTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7775007 | 0.75 | MAPT (0.42) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL3674710 | 0.75 | LIPG (0.47) | HTTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8560261 | 0.75 | MAPT (0.39) | ALDH1A1TDP1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685456-B1 | Bisquaternary ammonium derivatives of 2,2'-dimethyl-1,1'binaphtyl and process for their preparation | HOECHST AG (DE) | 1998-04-15 | — | — | EP | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |