Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557802 | 1.00 | DNM1 (0.44) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8599722 | 0.94 | HTT (0.36) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8555160 | 0.87 | MAPT (0.38) | ALDH1A1CYP1A2CYP2D6CYP2C19TSHR | |
| SCHEMBL8559212 | 0.81 | DNM1 (0.46) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL8553919 | 0.80 | MAPT (0.40) | ALDH1A1CYP1A2CYP2D6CYP2C19TSHR | |
| SCHEMBL3674710 | 0.79 | LIPG (0.47) | SMN1; SMN2MEN1KMT2AMAPK1TP53 | |
| SCHEMBL15536988 | 0.78 | TYR (0.42) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL16671703 | 0.77 | TLR8 (0.45) | SMN1; SMN2MEN1KMT2AMAPK1HTT | |
| SCHEMBL10106100 | 0.75 | DNM1 (0.42) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Tetrabuthylammonium SCHEMBL28415681 | 0.74 | KCNH2 (0.42) | SMN1; SMN2MEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685456-B1 | Bisquaternary ammonium derivatives of 2,2'-dimethyl-1,1'binaphtyl and process for their preparation | HOECHST AG (DE) | 1998-04-15 | — | — | EP | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |