Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560617 | 0.90 | AVPR1A (0.49) | AVPR2AVPR1AJAK2TYK2 | |
| SCHEMBL8558188 | 0.89 | NPC1 (0.47) | AVPR2AVPR1AJAK2KMT2A | |
| SCHEMBL8564681 | 0.87 | AVPR2 (0.42) | AVPR2AVPR1AJAK2JAK1TYK2 | |
| SCHEMBL8562470 | 0.86 | AVPR2 (0.40) | AVPR2AVPR1AJAK2JAK1TYK2 | |
| SCHEMBL8561396 | 0.85 | AVPR2 (0.42) | AVPR2AVPR1A | |
| SCHEMBL8563047 | 0.85 | AVPR1A (0.51) | AVPR1AKMT2A | |
| SCHEMBL8563496 | 0.84 | AVPR2 (0.56) | AVPR2AVPR1AKMT2A | |
| SCHEMBL8558117 | 0.84 | AVPR2 (0.47) | AVPR2AVPR1AJAK2JAK1TYK2 | |
| SCHEMBL8562616 | 0.84 | ITGB1 (0.40) | AVPR2AVPR1AJAK2JAK1TYK2 | |
| SCHEMBL8562938 | 0.83 | AVPR2 (0.45) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |