Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557610 | 0.90 | MAPT (0.52) | AVPR1ARAB9AKDM4EMAPK1MAPT | |
| SCHEMBL8559231 | 0.85 | AVPR2 (0.49) | AVPR1AKMT2A | |
| SCHEMBL8563394 | 0.84 | NPC1 (0.50) | AVPR1ARAB9AKDM4EMAPTNAMPT | |
| SCHEMBL8563203 | 0.84 | MEN1 (0.47) | KDM4EMAPK1GAAMAPTGFER | |
| SCHEMBL8563279 | 0.83 | AVPR2 (0.48) | AVPR1AKMT2A | |
| SCHEMBL8559901 | 0.81 | AVPR2 (0.63) | AVPR1A | |
| SCHEMBL8562420 | 0.81 | AVPR2 (0.46) | AVPR1ARAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8558298 | 0.80 | AVPR2 (0.55) | AVPR1A | |
| SCHEMBL8556562 | 0.80 | KCNK3 (0.44) | AVPR1ANAMPT | |
| SCHEMBL8562249 | 0.80 | AVPR2 (0.45) | AVPR1AMAPTTSHRNAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |