Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562470 | 0.92 | AVPR2 (0.40) | AVPR2AVPR1AJAK2TYK2JAK1 | |
| SCHEMBL8559867 | 0.91 | RAB9A (0.47) | AVPR2AVPR1A | |
| SCHEMBL8556908 | 0.90 | RAB9A (0.47) | AVPR2AVPR1AJAK2JAK1 | |
| SCHEMBL8561432 | 0.88 | AVPR2 (0.55) | AVPR2AVPR1AJAK2TYK2JAK1 | |
| SCHEMBL8558246 | 0.88 | AVPR2 (0.48) | AVPR2AVPR1ATYK2HPGD | |
| SCHEMBL8559231 | 0.87 | AVPR2 (0.49) | AVPR2AVPR1AJAK2TYK2JAK1 | |
| SCHEMBL8556938 | 0.87 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8561421 | 0.87 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL8557265 | 0.86 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8561799 | 0.85 | AVPR2 (0.59) | AVPR2AVPR1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |