Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564493 | 0.88 | KCNJ5 (0.46) | ROCK2L3MBTL1 | |
| SCHEMBL8563203 | 0.88 | MEN1 (0.47) | KMT2AMEN1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL8560108 | 0.87 | AVPR2 (0.38) | KMT2AMEN1AVPR2AVPR1APOLB | |
| SCHEMBL8559128 | 0.87 | AVPR1A (0.37) | AVPR2AVPR1APOLBALDH1A1NPSR1 | |
| SCHEMBL8563655 | 0.85 | AVPR1A (0.40) | KMT2AMEN1AVPR2AVPR1APOLB | |
| SCHEMBL8559901 | 0.83 | AVPR2 (0.63) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558298 | 0.80 | AVPR2 (0.55) | AVPR2AVPR1AOXTR | |
| SCHEMBL8562420 | 0.79 | AVPR2 (0.46) | KMT2AMEN1AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8558783 | 0.78 | PKM (0.50) | KMT2AMEN1AVPR2AVPR1A | |
| SCHEMBL8561211 | 0.78 | GRM1 (0.48) | KMT2AMEN1AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |