Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 4/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559426 | 0.88 | KMT2A (0.46) | ROCK2L3MBTL1 | |
| SCHEMBL8563203 | 0.86 | MEN1 (0.47) | SMN1; SMN2L3MBTL1NAMPTMAPT | |
| SCHEMBL8560108 | 0.83 | AVPR2 (0.38) | NPC1MAPTRAB9A | |
| SCHEMBL8559128 | 0.83 | AVPR1A (0.37) | MAPT | |
| SCHEMBL8560617 | 0.83 | AVPR1A (0.49) | SMN1; SMN2L3MBTL1MAPTRAB9A | |
| SCHEMBL8559231 | 0.83 | AVPR2 (0.49) | — | |
| SCHEMBL8558188 | 0.80 | NPC1 (0.47) | NPC1RAB9A | |
| SCHEMBL8563655 | 0.79 | AVPR1A (0.40) | NPC1MAPTRAB9A | |
| SCHEMBL8561396 | 0.79 | AVPR2 (0.42) | MAPT | |
| SCHEMBL8563496 | 0.78 | AVPR2 (0.56) | NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |