Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559426 | 0.88 | KMT2A (0.46) | MEN1KMT2AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL8564493 | 0.86 | KCNJ5 (0.46) | NAMPTL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8557610 | 0.84 | MAPT (0.52) | KMT2AGFERKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8563047 | 0.84 | AVPR1A (0.51) | KMT2ATSHRGAAGFERKDM4E | |
| SCHEMBL8559128 | 0.83 | AVPR1A (0.37) | MAPTALDH1A1NPSR1 | |
| SCHEMBL8560108 | 0.83 | AVPR2 (0.38) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL8563655 | 0.79 | AVPR1A (0.40) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL8563394 | 0.78 | NPC1 (0.50) | MEN1KMT2AKDM4ENAMPTMAPT | |
| SCHEMBL8563279 | 0.78 | AVPR2 (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8559901 | 0.75 | AVPR2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |