Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GLS | O94925 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8132955 | 0.80 | SMN1; SMN2 (0.69) | GAAKMT2ARAB9ANPC1POLB | |
| SCHEMBL8554413 | 0.80 | LMNA (0.65) | GAAGLAKMT2AGLSRAB9A | |
| SCHEMBL8554412 | 0.79 | NPC1 (0.64) | GAAGLAKMT2AGLSRAB9A | |
| SCHEMBL8118503 | 0.77 | MAPT (0.64) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11250062 | 0.72 | ALDH1A1 (0.80) | GAAKMT2AGLSRAB9ANPC1 | |
| SCHEMBL24440954 | 0.71 | ALDH1A1 (0.56) | GAAGLAKMT2AGLSRAB9A | |
| SCHEMBL8125122 | 0.71 | SMN1; SMN2 (0.60) | KMT2ARAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL8117715 | 0.71 | RAB9A (0.70) | KMT2ARAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL4318844 | 0.71 | SMN1; SMN2 (0.64) | GAARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27806628 | 0.70 | GLS (0.56) | GAAGLAKMT2AGLSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830349-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996039393-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-12 | — | — | WO | claimed |