Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.46 |
| ▸ | FASN | P49327 | 4/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407569 | 0.88 | CCNK (0.51) | CCNKCDK12NOS1NOS2FASN | |
| SCHEMBL8949110 | 0.86 | FASN (0.41) | CCNKCDK12PRKAA2PRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL8949289 | 0.82 | ITGB3 (0.45) | — | |
| SCHEMBL8560134 | 0.82 | KDM1A (0.49) | CCNKCDK12NOS1NOS2EGLN1 | |
| Hydrochloric Acid SCHEMBL8949069 | 0.80 | ITGB3 (0.43) | — | |
| SCHEMBL8948984 | 0.80 | FASN (0.42) | EGLN1FASN | |
| SCHEMBL8719948 | 0.78 | KDM1A (0.49) | CCNKCDK12NOS1NOS2FASN | |
| SCHEMBL8718956 | 0.78 | MLNR (0.48) | — | |
| SCHEMBL9267370 | 0.77 | EGLN1 (0.38) | EGLN1 | |
| SCHEMBL7674090 | 0.76 | RAB9A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |