Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | USP19 | O94966 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561935 | 0.90 | CA12 (0.38) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4405116 | 0.86 | PTGS2 (0.44) | F10TRPV1ALOX5APFEN1PTGS2 | |
| SCHEMBL8154449 | 0.85 | PTGES2 (0.45) | F10TRPV1ALOX5APFEN1CA12 | |
| SCHEMBL7501561 | 0.81 | PTGS2 (0.54) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL7502720 | 0.81 | PTGS2 (0.54) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8556828 | 0.80 | USP1 (0.39) | F10NR4A2USP1USP19WDR48 | |
| SCHEMBL8154083 | 0.79 | PTGS2 (0.42) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL8589897 | 0.79 | NR4A2 (0.40) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8555990 | 0.78 | NR4A2 (0.62) | F10NR4A2USP1USP19WDR48 | |
| SCHEMBL8555628 | 0.78 | USP1 (0.57) | TRPV1USP1USP19WDR48CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |