Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | USP19 | O94966 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.38 |
| ▸ | FEN1 | P39748 | 4/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561383 | 0.90 | USP1 (0.39) | USP1USP19WDR48ALOX5APFEN1 | |
| SCHEMBL8547032 | 0.85 | NR4A2 (0.38) | USP1USP19WDR48NR4A2PTGS2 | |
| SCHEMBL7499215 | 0.81 | PTGS2 (0.54) | CA1CA2CA12CA9PTGS2 | |
| SCHEMBL7508511 | 0.81 | PTGS2 (0.54) | CA1CA2CA12CA9PTGS2 | |
| SCHEMBL8560253 | 0.80 | F10 (0.37) | USP1USP19WDR48ALOX5APFEN1 | |
| SCHEMBL8555990 | 0.78 | NR4A2 (0.62) | USP1USP19WDR48NR4A2CA1 | |
| SCHEMBL8555628 | 0.78 | USP1 (0.57) | USP1USP19WDR48CA1CA2 | |
| SCHEMBL8139880 | 0.77 | NR4A2 (0.55) | NR4A2PTGS2RXRARXRBKDM4E | |
| SCHEMBL8557933 | 0.77 | NR4A2 (0.47) | NR4A2PTGS2RXRARXRBKDM4E | |
| SCHEMBL8560633 | 0.77 | RXRA (0.47) | NR4A2PTGS2RXRARXRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |