Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.60 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.58 |
| ▸ | OXTR | P30559 | 2/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335198 | 0.89 | AVPR1A (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL8556989 | 0.87 | AVPR1A (0.72) | AVPR1AAVPR2OXTR | |
| SCHEMBL8562670 | 0.87 | AVPR1A (0.60) | AVPR1AAVPR2OXTR | |
| SCHEMBL8562680 | 0.85 | ALDH1A1 (0.59) | AVPR1AAVPR2OXTRNAMPT | |
| SCHEMBL8557460 | 0.85 | AVPR1A (0.64) | AVPR1AAVPR2OXTR | |
| SCHEMBL6990495 | 0.85 | AVPR2 (0.58) | AVPR1AAVPR2OXTR | |
| SCHEMBL8558289 | 0.85 | AVPR2 (0.60) | AVPR1AAVPR2OXTR | |
| SCHEMBL8560409 | 0.84 | AVPR2 (0.53) | AVPR1AAVPR2OXTRNAMPT | |
| SCHEMBL8559859 | 0.82 | AVPR2 (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL8558930 | 0.82 | AVPR2 (0.60) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |