Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.36 |
| ▸ | FEN1 | P39748 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556639 | 0.95 | FAAH (0.36) | FAAHMAPTALDH1A1MEN1ELANE | |
| SCHEMBL8559668 | 0.91 | ALPL (0.36) | FAAHMAPTALDH1A1MEN1ELANE | |
| SCHEMBL8555192 | 0.90 | POLB (0.37) | FAAHMAPTALDH1A1ALOX5APFEN1 | |
| SCHEMBL8560601 | 0.90 | ALOX5AP (0.41) | FAAHMAPTALDH1A1ALOX5APFEN1 | |
| SCHEMBL8555128 | 0.90 | MAPT (0.35) | FAAHMAPTALDH1A1MEN1ELANE | |
| SCHEMBL8557881 | 0.89 | ALPL (0.36) | FAAHMAPTALDH1A1MEN1ELANE | |
| SCHEMBL8559362 | 0.88 | ALOX5AP (0.40) | FAAHMAPTALDH1A1ALOX5APFEN1 | |
| SCHEMBL8561143 | 0.88 | POLB (0.37) | FAAHMAPTALDH1A1ALOX5APFEN1 | |
| SCHEMBL8556834 | 0.88 | MAPT (0.35) | FAAHMAPTALDH1A1MEN1ELANE | |
| SCHEMBL8557786 | 0.88 | CA12 (0.37) | FAAHMAPTALDH1A1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |