Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561143 | 0.96 | POLB (0.37) | POLBALOX5APFEN1LTB4RLTB4R2 | |
| SCHEMBL8560601 | 0.92 | ALOX5AP (0.41) | POLBALOX5APFEN1LTB4RLTB4R2 | |
| SCHEMBL8560516 | 0.90 | FAAH (0.36) | ALOX5APFEN1CA12CA1CA2 | |
| SCHEMBL8559922 | 0.90 | ALOX5AP (0.41) | POLBALOX5APFEN1LTB4RLTB4R2 | |
| SCHEMBL8556639 | 0.88 | FAAH (0.36) | ALOX5APFEN1CA12CA1CA2 | |
| SCHEMBL8559713 | 0.88 | FABP1 (0.38) | ALOX5APFEN1LTB4RLTB4R2PTGS1 | |
| SCHEMBL8561129 | 0.86 | PTGS2 (0.44) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL8558356 | 0.86 | FABP1 (0.38) | ALOX5APFEN1LTB4RLTB4R2PTGS1 | |
| SCHEMBL8556529 | 0.85 | RXRA (0.40) | POLBALOX5APFEN1LTB4RLTB4R2 | |
| SCHEMBL8557992 | 0.85 | ALOX5AP (0.41) | ALOX5APFEN1PTGS1PTGS2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |