Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560875 | 0.74 | MEN1 (0.36) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL8556883 | 0.71 | PDK2 (0.40) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL20088306 | 0.67 | IMPDH2 (0.34) | ALDH1A1NPSR1HPGDKDM4EGLA | |
| SCHEMBL8554202 | 0.67 | MEN1 (0.35) | ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL8598630 | 0.66 | MEN1 (0.34) | HPGDKDM4EGAA | |
| SCHEMBL8555558 | 0.65 | GABRA1 (0.42) | NPSR1HPGDKDM4EGAAL3MBTL1 | |
| SCHEMBL5810793 | 0.63 | KDM4E (0.39) | ALDH1A1NPSR1HPGDKDM4EGLA | |
| SCHEMBL8555174 | 0.62 | PDK2 (0.31) | — | |
| SCHEMBL8556416 | 0.62 | — | — | |
| SCHEMBL8557831 | 0.62 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |