Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 7/20 | 0.44 |
| ▸ | EDNRA | P25101 | 7/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025116 | 0.92 | MAPT (0.42) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8559259 | 0.92 | MAPT (0.47) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL9025734 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8559393 | 0.91 | KMO (0.47) | ALDH1A1MAPTLMNASLC40A1TSHR | |
| SCHEMBL8561399 | 0.91 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8556990 | 0.88 | MAPT (0.47) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8559468 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASLC40A1TSHR | |
| SCHEMBL9026338 | 0.87 | LMNA (0.49) | ALDH1A1MAPTLMNATSHRLIMK2 | |
| SCHEMBL8557213 | 0.86 | MAPT (0.47) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8561122 | 0.85 | MAPT (0.44) | ALDH1A1MAPTLMNASLC40A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |