Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821781 | 0.81 | NPC1 (0.41) | MEN1KMT2APDE10APOLBS1PR4 | |
| SCHEMBL12040240 | 0.81 | L3MBTL1 (0.40) | MEN1KMT2APDE10APOLBS1PR4 | |
| SCHEMBL28246029 | 0.79 | ALDH1A1 (0.40) | HSD11B1MEN1KMT2APOLBS1PR4 | |
| SCHEMBL7014776 | 0.79 | KMT2A (0.43) | MEN1KMT2APDE10APOLBS1PR4 | |
| SCHEMBL488499 | 0.77 | KMT2A (0.56) | MEN1KMT2APOLBS1PR4NPC1 | |
| SCHEMBL28058098 | 0.75 | ALDH1A1 (0.37) | HSD11B1TRPV1MEN1KMT2APOLB | |
| SCHEMBL8562204 | 0.75 | S1PR4 (0.38) | HSD11B1POLBS1PR4ALDH1A1KDM4E | |
| SCHEMBL8565240 | 0.75 | KMT2A (0.51) | MEN1KMT2APOLBS1PR4NPC1 | |
| SCHEMBL31481294 | 0.75 | ALDH1A1 (0.37) | HSD11B1TRPV1MEN1KMT2APOLB | |
| SCHEMBL15616516 | 0.75 | KMT2A (0.55) | MEN1KMT2APOLBS1PR4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314646-A | A kind of method of high dispersive bimetal nano material preparation urogenital system pharmaceutical intermediate | 胡鹏 | 2018-07-24 | — | — | CN | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-3937831-A | CHLOROMETHYL NITROPYRIDINES AS ANTIMICROBIALS | THE DOW CHEMICAL COMPANY (US) | 1976-02-10 | — | — | US | disclosed |