Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560593 | 0.79 | HSD11B1 (0.44) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL5643188 | 0.77 | PDE10A (0.48) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL29579675 | 0.77 | PDE10A (0.58) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL294121 | 0.77 | PDE10A (0.58) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL251801 | 0.75 | MAPT (0.45) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL5700168 | 0.75 | MEN1 (0.43) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL799695 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1PDE10APOLBALDH1A1 | |
| SCHEMBL21847263 | 0.75 | KMT2A (0.43) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL601835 | 0.75 | HTT (0.50) | KMT2AMEN1PDE10APOLBNPC1 | |
| SCHEMBL541486 | 0.75 | NPC1 (0.51) | KMT2AMEN1PDE10APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998584-B2 | Conjugate of a tubulysin analog with branched linkers | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2024-06-04 | — | — | US | disclosed |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| CN-103497177-B | Amino heterocyclic aromatic compound serving as c-Met inhibitor, and preparation method thereof | 天津滨江药物研发有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-8952002-B2 | Aminoheteroaryl compounds and preparation method and use thereof | SHANGHAI ALLIST PHARMACEUTICALS, INC. (CN) | 2015-02-10 | — | — | US | disclosed |
| US-8952002-B2 | Aminoheteroaryl compounds and preparation method and use thereof | SHANGHAI ALLIST PHARMACEUTICALS, INC. (CN) | 2015-02-10 | — | — | US | disclosed |
| US-20140357613-A1 | Aminoheteroaryl compounds and preparation method and use thereof | SHANGHAI ALLIST PHARMACEUTICALS, INC. (CN) | 2014-12-04 | — | — | US | disclosed |
| US-20140357613-A1 | Aminoheteroaryl compounds and preparation method and use thereof | SHANGHAI ALLIST PHARMACEUTICALS, INC. (CN) | 2014-12-04 | — | — | US | disclosed |
| WO-2013107285-A1 | AMINO HETEROARYL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技有限公司 (CN) | 2013-07-25 | — | — | WO | disclosed |
| EP-0662078-B1 | REAGENTS FOR PEPTIDE COUPLINGS | RES CORP TECHNOLOGIES INC (US) | 2003-05-02 | — | — | EP | disclosed |
| US-RE38073-E1 | Biosynthesis; using dehydration agent | RESEARCH CORPORATIONS TECHNOLOGIES, INC. | 2003-04-08 | — | — | US | disclosed |
| US-RE37686-E1 | Azahydroxybenzotriazoles and derivatives thereof for peptide coupling reactions | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5698675-A | AMIDATION; ESTERIFICATION | RESEARCH CORPORATION TECH., INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| US-5644029-A | TRIAZOLO-PYRIDINE HETEROCYCLIC COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5580981-A | YELLOW INDICATORS FADING TO COLORLESS UPON COMPLETION OF THE ACYLATION STEP IN AMIDE FORMATION; REACTION ACCELERATORS; LOWERS RACEMIZATION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0662078-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994007910-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357613-A1 | Aminoheteroaryl compounds and preparation method and use thereof | MET, HGF, HDGF | KMT2A 1475/4885MEN1 560/4885PDE10A 4655/4885 |
| US-11998584-B2 | Conjugate of a tubulysin analog with branched linkers | TEKT1, TEK, CD2BP2 | KMT2A 2786/4885MEN1 245/4885PDE10A 4815/4885 |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, TEK, BTN3A1 | KMT2A 2842/4885MEN1 281/4885PDE10A 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.