Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31481294 | 0.79 | ALDH1A1 (0.37) | S1PR4ALDH1A1HSD11B1MAPTPOLB | |
| SCHEMBL28058098 | 0.79 | ALDH1A1 (0.37) | S1PR4ALDH1A1HSD11B1MAPTPOLB | |
| SCHEMBL28246029 | 0.79 | ALDH1A1 (0.40) | S1PR4ALDH1A1HSD11B1MAPTPOLB | |
| SCHEMBL8567050 | 0.77 | ROCK1 (0.34) | S1PR4ALDH1A1ROCK1MAPTPOLB | |
| SCHEMBL8565404 | 0.76 | MAPT (0.42) | ALDH1A1PDE7AMAPTLMNAKDM4E | |
| SCHEMBL8141010 | 0.76 | HTT (0.37) | ALDH1A1ROCK1MAPTPOLBLMNA | |
| SCHEMBL8568195 | 0.76 | KMT2A (0.36) | S1PR4ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL8560593 | 0.75 | HSD11B1 (0.44) | S1PR4ALDH1A1HSD11B1MAPTPOLB | |
| SCHEMBL8564386 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL3218043 | 0.73 | NOS3 (0.50) | ALDH1A1NOS3NOS2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |