Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561414 | 0.93 | PTGS2 (0.47) | PTGS2PTGS1L3MBTL1CYP17A1MAPT | |
| SCHEMBL8559432 | 0.92 | MAPK1 (0.40) | L3MBTL1MAPTRXRASCN9A | |
| SCHEMBL8560188 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1MAPTRXRASCN9A | |
| SCHEMBL8554948 | 0.88 | PTGS2 (0.42) | PTGS2PTGS1ALOX5APFEN1RXRA | |
| SCHEMBL8558565 | 0.88 | PTGS2 (0.44) | PTGS2PTGS1MAPTALOX5APFEN1 | |
| SCHEMBL8555759 | 0.87 | PTGS2 (0.39) | PTGS2PTGS1L3MBTL1MAPTRXRA | |
| SCHEMBL7501679 | 0.87 | PTGS2 (0.55) | PTGS2PTGS1MAPT | |
| SCHEMBL8559238 | 0.86 | PTGS2 (0.42) | PTGS2PTGS1MAPTALOX5APFEN1 | |
| SCHEMBL7505035 | 0.85 | PTGS2 (0.57) | PTGS2PTGS1MAPT | |
| SCHEMBL8556976 | 0.84 | SCN9A (0.44) | L3MBTL1MAPTRXRASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |