Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.41 |
| ▸ | FEN1 | P39748 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557992 | 0.92 | ALOX5AP (0.41) | PTGS2PTGS1ALOX5APFEN1F10 | |
| SCHEMBL8559238 | 0.91 | PTGS2 (0.42) | PTGS2PTGS1ALOX5APFEN1F10 | |
| SCHEMBL8558565 | 0.91 | PTGS2 (0.44) | PTGS2PTGS1ALOX5APFEN1F10 | |
| SCHEMBL8560736 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1ALOX5APFEN1SCN9A | |
| SCHEMBL8559710 | 0.88 | PTGS2 (0.42) | PTGS2PTGS1ALOX5APFEN1SCN9A | |
| SCHEMBL8557001 | 0.88 | RXRA (0.40) | PTGS2PTGS1ALOX5APFEN1F10 | |
| SCHEMBL8555554 | 0.87 | RXRA (0.47) | PTGS2PTGS1ALOX5APFEN1SCN9A | |
| SCHEMBL8557473 | 0.87 | NR4A2 (0.44) | PTGS2PTGS1SCN9ARXRARXRB | |
| SCHEMBL8560340 | 0.86 | RXRA (0.46) | PTGS2PTGS1F10RXRARXRB | |
| SCHEMBL8556639 | 0.86 | FAAH (0.36) | ALOX5APFEN1SCN9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |