Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560783 | 1.00 | HTT (0.47) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL25244867 | 0.82 | L3MBTL1 (0.47) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL8485479 | 0.82 | ALDH1A1 (0.47) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL5843840 | 0.78 | L3MBTL1 (0.56) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL13120844 | 0.77 | ALDH1A1 (0.46) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL14303528 | 0.77 | HRH3 (0.48) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL8564268 | 0.74 | DDB1 (0.50) | L3MBTL1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8564264 | 0.74 | DDB1 (0.50) | L3MBTL1ALDH1A1TSHRMEN1KMT2A | |
| Bromide SCHEMBL7887350 | 0.74 | L3MBTL1 (0.43) | HTTL3MBTL1ALDH1A1KDM4ETSHR | |
| SCHEMBL7050984 | 0.71 | HTT (0.72) | HTTALDH1A1KDM4ETSHRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |