Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559349 | 0.86 | AVPR2 (0.60) | ACHEAVPR2AVPR1A | |
| SCHEMBL8560873 | 0.84 | ACHE (0.60) | ACHEAVPR2AVPR1ARAB9AHSD17B3 | |
| SCHEMBL8561645 | 0.84 | AVPR2 (0.58) | ACHEAVPR2AVPR1ANPC1RAB9A | |
| SCHEMBL8559546 | 0.84 | AVPR2 (0.55) | ACHEAVPR2AVPR1AHSD17B3 | |
| SCHEMBL7357183 | 0.83 | RAB9A (0.65) | AVPR2AVPR1ARAB9A | |
| SCHEMBL8563019 | 0.83 | AVPR2 (0.59) | ACHEAVPR2AVPR1A | |
| SCHEMBL8563344 | 0.82 | AVPR2 (0.81) | AVPR2AVPR1A | |
| SCHEMBL8558027 | 0.82 | AVPR2 (0.69) | AVPR2AVPR1A | |
| SCHEMBL8558377 | 0.82 | NAMPT (0.54) | ACHEAVPR2AVPR1ANPC1RAB9A | |
| SCHEMBL8556851 | 0.81 | AVPR2 (0.58) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |