Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780531 | 0.81 | RORC (0.44) | ALDH1A1KDM4EHSD17B10KMORORC | |
| SCHEMBL8564952 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10KMODPP4 | |
| SCHEMBL27649565 | 0.79 | RORC (0.51) | ALDH1A1KDM4EHSD17B10KMORORC | |
| SCHEMBL7299393 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10ELANEKMT2A | |
| SCHEMBL2617466 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KMORORCKMT2ACSNK2A1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL117071 | 0.72 | DPP4 (0.62) | ALDH1A1KDM4EHSD17B10DPP4CSNK2A1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL29365114 | 0.72 | DPP4 (0.62) | ALDH1A1KDM4EHSD17B10DPP4CSNK2A1 | |
| SCHEMBL21121080 | 0.72 | IRAK4 (0.53) | ALDH1A1KDM4EHSD17B10KMOKMT2A | |
| SCHEMBL403840 | 0.72 | RORC (0.56) | ALDH1A1KDM4EKMORORCKMT2A | |
| SCHEMBL15658321 | 0.72 | TSHR (0.53) | ALDH1A1KDM4EKMORORCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |