Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561230 | 0.89 | AVPR1A (0.46) | MAPTTP53AVPR2AVPR1APOLB | |
| SCHEMBL8557883 | 0.87 | MEN1 (0.50) | MAPTTP53AVPR2AVPR1AAKT1 | |
| SCHEMBL8559689 | 0.86 | LMNA (0.53) | MAPTRXFP1POLBLMNAMEN1 | |
| SCHEMBL8558194 | 0.85 | AKT1 (0.52) | MAPTTP53AKT1AURKALMNA | |
| SCHEMBL8562066 | 0.85 | AURKA (0.47) | MAPTTP53AVPR2AVPR1ARXFP1 | |
| SCHEMBL8562449 | 0.84 | AVPR2 (0.46) | TP53AVPR2AVPR1ARXFP1AURKA | |
| SCHEMBL8559861 | 0.84 | AURKA (0.47) | AVPR2AVPR1AAKT1AURKARET | |
| SCHEMBL8559885 | 0.83 | AVPR2 (0.46) | AVPR2AVPR1AAURKA | |
| SCHEMBL8562616 | 0.81 | ITGB1 (0.40) | TP53AVPR2AVPR1AAKT1MEN1 | |
| SCHEMBL8557390 | 0.81 | AVPR2 (0.52) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |