Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320103 | 0.83 | GABRP (0.48) | ALDH1A1CES2GPR35TLR7HPGD | |
| SCHEMBL3740447 | 0.81 | CES2 (0.43) | ALDH1A1CES2GPR35TLR7HPGD | |
| SCHEMBL22093115 | 0.81 | GAA (0.45) | ALDH1A1CES2GPR35TLR7GAA | |
| SCHEMBL29096054 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TSHR | |
| SCHEMBL16408244 | 0.78 | CES2 (0.45) | ALDH1A1CES2GPR35TLR7JUN | |
| SCHEMBL18394005 | 0.78 | CES2 (0.47) | CES2GPR35JUNNFKB1NFKB2 | |
| SCHEMBL42960 | 0.78 | DDR1 (0.44) | ALDH1A1CES2GPR35TLR7HPGD | |
| SCHEMBL28208232 | 0.78 | CES2 (0.41) | ALDH1A1CES2GPR35HPGDJUN | |
| SCHEMBL27816993 | 0.78 | GPR35 (0.42) | ALDH1A1CES2GPR35HPGDJUN | |
| SCHEMBL5724990 | 0.76 | GSK3B (0.50) | ALDH1A1CES2GPR35TLR7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739083-A | LOW IN TOXICITY AND PERSISTENCE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0802191-A1 | PYRAZOLE DERIVATIVES AND INSECTICIDAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-10-22 | — | — | EP | disclosed |