Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561020 | 0.92 | RXRA (0.52) | RXRARXRBF10RAB9AMAPT | |
| SCHEMBL8556108 | 0.92 | RXRA (0.41) | RXRARXRBMEN1KMT2AP2RX3 | |
| SCHEMBL8556976 | 0.91 | SCN9A (0.44) | RXRARXRBMEN1KMT2ASCN9A | |
| SCHEMBL8555918 | 0.87 | RXRA (0.38) | RXRARXRBMAPTALDH1A1RXRG | |
| SCHEMBL8558000 | 0.86 | RXRA (0.47) | RXRARXRBMEN1KMT2ASCN9A | |
| SCHEMBL8559432 | 0.86 | MAPK1 (0.40) | RXRAMEN1KMT2ASCN9ARAB9A | |
| SCHEMBL8556294 | 0.86 | RXRA (0.49) | RXRARXRBKMT2AF10RAB9A | |
| SCHEMBL8553428 | 0.86 | CA1 (0.42) | RXRAMEN1KMT2AP2RX3MAPT | |
| SCHEMBL8557473 | 0.86 | NR4A2 (0.44) | RXRARXRBMEN1KMT2ASCN9A | |
| SCHEMBL8559042 | 0.85 | L3MBTL1 (0.43) | RXRAMEN1KMT2AP2RX3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |