Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.38 |
| ▸ | RXRB | P28702 | 7/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558990 | 0.92 | NR4A2 (0.39) | RXRARXRBNR4A2ALDH1A1PTGS2 | |
| SCHEMBL8560188 | 0.89 | PTGS2 (0.47) | RXRARXRBNR4A2PTGS2PTGS1 | |
| SCHEMBL8553796 | 0.87 | NR4A2 (0.38) | RXRARXRBNR4A2ALDH1A1PTGS2 | |
| SCHEMBL8561649 | 0.87 | RXRA (0.41) | RXRARXRBALDH1A1RXRGMAPT | |
| SCHEMBL8555759 | 0.87 | PTGS2 (0.39) | RXRARXRBNR4A2PTGS2PTGS1 | |
| SCHEMBL8560006 | 0.86 | RXRA (0.48) | RXRARXRBNR4A2PTGS2PTGS1 | |
| SCHEMBL8556041 | 0.86 | RXRA (0.47) | RXRARXRBNR4A2ALDH1A1RXRG | |
| SCHEMBL8555989 | 0.85 | NR4A2 (0.38) | RXRARXRBNR4A2ALDH1A1PTGS2 | |
| SCHEMBL7499408 | 0.85 | PTGS2 (0.47) | RXRARXRBALDH1A1PTGS2PTGS1 | |
| SCHEMBL8559701 | 0.85 | RXRA (0.39) | RXRARXRBNR4A2ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |