Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560691 | 0.97 | CA1 (0.41) | CA1CA2CA9CA13RXRA | |
| SCHEMBL8559042 | 0.93 | L3MBTL1 (0.43) | CA1CA2CA9CA13RXRA | |
| SCHEMBL8557664 | 0.91 | L3MBTL1 (0.43) | CA1CA2CA9CA13RXRA | |
| SCHEMBL8559802 | 0.91 | RXRA (0.49) | CA1CA2CA9RXRAALDH1A1 | |
| SCHEMBL8557954 | 0.89 | RXRA (0.47) | CA1CA2CA9RXRAALDH1A1 | |
| SCHEMBL8556827 | 0.89 | GRM2 (0.42) | CA1CA2CA9CA13RXRA | |
| SCHEMBL8555295 | 0.89 | NR4A2 (0.36) | CA1CA2CA9RXRAMAPT | |
| SCHEMBL8556320 | 0.87 | GRM2 (0.42) | CA1CA2CA9RXRAALDH1A1 | |
| SCHEMBL8556976 | 0.87 | SCN9A (0.44) | RXRAALDH1A1L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL8554223 | 0.87 | GPR55 (0.36) | CA1CA2CA9RXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |