Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131373 | 0.86 | ALDH1A1 (0.53) | TP53TSHRALDH1A1MAPTHPGD | |
| SCHEMBL13005355 | 0.84 | ALDH1A1 (0.54) | THRBTP53TSHRALDH1A1MAPT | |
| SCHEMBL10691467 | 0.82 | ESR1 (0.58) | TP53TSHRALDH1A1MAPTHPGD | |
| SCHEMBL7603904 | 0.81 | ALDH1A1 (0.50) | THRBTP53TSHRALDH1A1MAPT | |
| SCHEMBL6757523 | 0.80 | KMT2A (0.45) | TP53TSHRALDH1A1MAPTHPGD | |
| SCHEMBL4437074 | 0.80 | TDP1 (0.59) | TP53TSHRALDH1A1MAPTHPGD | |
| SCHEMBL4437068 | 0.80 | TDP1 (0.59) | TP53TSHRALDH1A1MAPTHPGD | |
| SCHEMBL1395971 | 0.78 | THRB (0.54) | THRBMEN1KMT2APPARGESR1 | |
| SCHEMBL966896 | 0.78 | ALDH1A1 (0.70) | THRBTP53TSHRALDH1A1MAPT | |
| SCHEMBL28865920 | 0.78 | ALDH1A1 (0.58) | TP53TSHRALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741543-A | CONTAINING UNSATURATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |