Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998537 | 0.83 | CES2 (0.55) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL2956379 | 0.83 | RAB9A (0.55) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL6197413 | 0.81 | RAB9A (0.56) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL26056789 | 0.80 | CES2 (0.66) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL1937375 | 0.78 | RAB9A (0.58) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL3999322 | 0.78 | CES2 (0.58) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL619898 | 0.78 | CES2 (0.64) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL28063686 | 0.77 | HPGDS (0.58) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL7823510 | 0.77 | DAO (0.50) | CES2CES1KEAP1DAORAB9A | |
| SCHEMBL23793030 | 0.77 | RAB9A (0.56) | CES2CES1KEAP1DAORAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62190105-A | — | — | None | — | — | JP | disclosed |
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5623073-A | ANTIDIABETIC AGENT | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |
| JP-S62190105-A | SLIME CONTROLLER FOR PAPER MAKING | KANAGAWA PREF GOV | 1987-08-20 | — | — | JP | disclosed |
| US-4266067-A | Process for preparing thiophene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-05-05 | — | — | US | disclosed |
| US-4219659-A | Process for the preparation of thiophene derivatives and thiophene derivatives obtained therethrough | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-08-26 | — | — | US | disclosed |