Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564098 | 0.93 | OPRK1 (0.50) | KDM1ACCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL6166988 | 0.92 | OPRK1 (0.49) | KDM1ACCR5KCNH2 | |
| SCHEMBL8568883 | 0.90 | KDM1A (0.47) | KDM1AKMT2ASIGMAR1KCNH2MEN1 | |
| SCHEMBL8571953 | 0.89 | KDM1A (0.44) | KDM1ACCR5KMT2ASIGMAR1OPRL1 | |
| SCHEMBL6168606 | 0.89 | OPRL1 (0.52) | CYP2D6CYP2C9CCR5KMT2AOPRL1 | |
| SCHEMBL29445321 | 0.89 | OPRL1 (0.52) | CYP2D6CYP2C9CCR5KMT2AOPRL1 | |
| SCHEMBL6164748 | 0.88 | OPRL1 (0.44) | KDM1AOPRL1 | |
| SCHEMBL8571871 | 0.88 | CHRM3 (0.54) | KDM1ASIGMAR1OPRL1 | |
| SCHEMBL8564439 | 0.87 | CHRM2 (0.55) | CYP2D6CYP2C9SIGMAR1OPRL1 | |
| SCHEMBL8570520 | 0.86 | OPRL1 (0.45) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |