Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571953 | 0.90 | KDM1A (0.44) | KDM1AKMT2AALDH1A1SMN1; SMN2OPRK1 | |
| SCHEMBL8562694 | 0.90 | KDM1A (0.56) | KDM1AKMT2AMEN1SIGMAR1KCNH2 | |
| SCHEMBL8564098 | 0.88 | OPRK1 (0.50) | KDM1AOPRM1OPRK1OPRD1KCNH2 | |
| Hydrochloric Acid SCHEMBL6166988 | 0.88 | OPRK1 (0.49) | KDM1AOPRM1OPRK1OPRD1KCNH2 | |
| SCHEMBL8570520 | 0.86 | OPRL1 (0.45) | OPRM1CHRM2DRD3 | |
| SCHEMBL6166931 | 0.85 | CHRM3 (0.43) | KMT2AMEN1OPRM1CCR8CHRM2 | |
| SCHEMBL8565700 | 0.85 | CHRM3 (0.56) | KMT2AALDH1A1OPRM1CCR8KDM4E | |
| SCHEMBL29445321 | 0.85 | OPRL1 (0.52) | KMT2AMEN1OPRM1OPRK1CHRM2 | |
| SCHEMBL6168606 | 0.85 | OPRL1 (0.52) | KMT2AMEN1OPRM1OPRK1CHRM2 | |
| SCHEMBL6164748 | 0.84 | OPRL1 (0.44) | KDM1AOPRM1OPRK1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |