SCHEMBL8562822

SCHEMBL8562822

O=C1C2=C(CCCC2)C(=O)N1c1cc(S)c(Cl)cc1F

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 1/20 0.44
GRM4 Q14833 1/20 0.44
PPOX P50336 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5318626 0.83 GRM7 (0.45) GRM7GRM4PPOX
SCHEMBL10719745 0.82 GRM7 (0.46) GRM7GRM4PPOX
SCHEMBL5318631 0.82 GRM7 (0.46) GRM7GRM4PPOX
SCHEMBL7770396 0.82 PPOX (0.45) GRM7GRM4PPOX
SCHEMBL30566778 0.82 GRM7 (0.46) GRM7GRM4PPOX
SCHEMBL7711642 0.79 GRM7 (0.42) GRM7GRM4PPOX
SCHEMBL10716791 0.79 PPOX (0.44) GRM7GRM4PPOX
SCHEMBL9736984 0.78 ALDH1A1 (0.44) GRM7GRM4
SCHEMBL9765563 0.78 GRM7 (0.47) GRM7GRM4
SCHEMBL10573081 0.78 GRM7 (0.44) GRM7GRM4PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548593-B1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient MITSUBISHI CHEM CORP (JP) 1998-04-22 EP disclosed
US-5405828-A Selective pre- and postemergence herbicides MITSUBISHI KASEI CORPORATION (JP) 1995-04-11 US disclosed
US-5324709-A Safety on crops MITSUBISHI KASEI CORPORATION (JP) 1994-06-28 US disclosed
EP-0548593-A1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient Mitsubishi Chemical Corporation (JP) 1993-06-30 EP disclosed