SCHEMBL7770396

SCHEMBL7770396

Nc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.45
GRM7 Q14831 1/20 0.44
GRM4 Q14833 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5318626 0.83 GRM7 (0.45) PPOXGRM7GRM4
SCHEMBL8562822 0.82 GRM7 (0.44) PPOXGRM7GRM4
SCHEMBL10535064 0.82 PPOX (0.44) PPOXGRM7GRM4
SCHEMBL10719745 0.82 GRM7 (0.46) PPOXGRM7GRM4
SCHEMBL30566778 0.82 GRM7 (0.46) PPOXGRM7GRM4
SCHEMBL5318631 0.82 GRM7 (0.46) PPOXGRM7GRM4
SCHEMBL9736832 0.80 GRM7 (0.46) GRM7GRM4
SCHEMBL7711642 0.79 GRM7 (0.42) PPOXGRM7GRM4
SCHEMBL10716791 0.79 PPOX (0.44) PPOXGRM7GRM4
SCHEMBL9736984 0.78 ALDH1A1 (0.44) GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59067261-A None JP disclosed
JP-58103363-A None JP disclosed
US-20240300932-A1 N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF GUIZHOU UNIVERSITY (CN) 2024-09-12 US disclosed
WO-2024174317-A1 N-PHENYLIMINE-CONTAINING DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 贵州大学 2024-08-29 WO disclosed
CN-116731003-A N-phenylimine-containing derivative, and preparation method and application thereof 贵州大学 2023-09-12 CN disclosed
EP-0834503-B1 Tetrahydrophthalimides, their preparation and use BASF AG (DE) 2001-06-27 EP disclosed
US-6204222-B1 SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-20 US disclosed
US-6175007-B1 HERBICIDES AND DEFOLIANTS BASF AKTIENGESELLSCHAFT (DE) 2001-01-16 US disclosed
US-5817603-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-06 US disclosed
EP-0548593-B1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient MITSUBISHI CHEM CORP (JP) 1998-04-22 EP disclosed
EP-0172306-B1 TETRAHYDROPHTHALIMIDE COMPOUNDS, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-07 EP disclosed
EP-0126419-B1 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP disclosed
US-4709049-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-24 US disclosed
US-4684397-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-04 US disclosed
EP-0172306-A1 Tetrahydrophthalimide compounds, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-26 EP disclosed
EP-0126419-A1 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-28 EP disclosed
JP-S5967261-A AMINOPHENYLTETRAHYDROPHTHALIMIDE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT SUMITOMO CHEM CO LTD 1984-04-16 JP disclosed
EP-0083055-A2 Tetrahydrophthalimide compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-06 EP disclosed
JP-S58103363-A TETRAHYDROPHTHALIMIDE AND HERBICIDE CONTAINING THE SAME AS ACTIVE CONSTITUENT MITSUBISHI CHEM IND LTD 1983-06-20 JP disclosed
EP-0077938-A2 N-(3-substituted aminophenyl) tetrahydrophthalimides and herbicidal composition MITSUBISHI KASEI CORPORATION (JP) 1983-05-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300932-A1 N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF PNMT, NNMT, PAH PPOX 65/4885GRM7 1512/4885GRM4 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.