SCHEMBL856286

SCHEMBL856286

CC(C)(C)OC(=O)NCC(O)CN

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
SYK P43405 1/20 0.39
SERPINE1 P05121 1/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA7 P43166 1/20 0.39
CYP2D6 P10635 1/20 0.38
CTSS P25774 3/20 0.38
CTSK P43235 3/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
AAK1 Q2M2I8 1/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
APLNR P35414 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852153 1.00 MEN1 (0.45) MEN1GAAKMT2ATDP1MAOA
SCHEMBL2852156 1.00 MEN1 (0.45) MEN1GAAKMT2ATDP1MAOA
SCHEMBL570033 0.88 MEN1 (0.50) MEN1GAAKMT2ATDP1MAOA
SCHEMBL21483554 0.86 MEN1 (0.46) MEN1GAAKMT2ATDP1MAOA
SCHEMBL3025341 0.84 MAOA (0.44) MEN1GAAKMT2ATDP1MAOA
SCHEMBL31236580 0.83 MEN1 (0.36) MEN1GAAKMT2ATDP1MAOA
SCHEMBL31236478 0.83 MEN1 (0.36) MEN1GAAKMT2ATDP1MAOA
SCHEMBL31236543 0.83 MEN1 (0.36) MEN1GAAKMT2ATDP1MAOA
SCHEMBL31236527 0.83 MEN1 (0.36) MEN1GAAKMT2ATDP1MAOA
SCHEMBL1222350 0.83 TDP1 (0.49) MEN1GAAKMT2ATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106893342-A A kind of dimethylbenzene green grass or young crops FF derivative dyes and its synthetic method 宁波普芯生物科技有限公司 2017-06-27 CN claimed
EP-4746963-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4743465-A1 BICYCLIC MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-20 EP disclosed
US-20260109732-A1 LIPID AMINES MODERNATX INC (US) 2026-04-23 US disclosed
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2025-07-24 US disclosed
WO-2025068132-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-04-03 WO disclosed
WO-2025021666-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-01-30 WO disclosed
WO-2025017045-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-01-23 WO disclosed
WO-2025012195-A1 BICYCLIC MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-01-16 WO disclosed
WO-2006009832-A1 SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-01-26 WO disclosed
WO-2005066172-A1 PIPERAZINE, [1,4]DIAZEPANE, [1,4]DIAZOCANE, AND [1,5]DIAZOCANE FUSED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-07-21 WO disclosed
WO-2003093346-A1 MULTIFUNCTIONAL POLYETHYLENE GLYCOL DERIVATIVES: PREPARATION AND USE UNIVERSITA' DEGLI STUDI DI TRIESTE (IT) 2003-11-13 WO disclosed
US-20020049191-A1 Cephalosporin derivatives BRISTOL-MYERS SQUIBB COMPANY 2002-04-25 US disclosed
US-5734047-A GRAM-POSITIVE ANTIBACTERIAL AGENT BRISTOL-MYERS SQUIBB COMPANY (US) 1998-03-31 US disclosed
WO-1997022611-A1 CEPHALOSPORIN DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 1997-06-26 WO disclosed
EP-0496561-B1 [[(2-Amino-3,4-dioxo-1-cyclobuten-1-yl)amino]alkyl]-acid derivatives AMERICAN HOME PROD (US) 1995-03-15 EP disclosed
US-5240946-A Anticonvulsants, nervous system disorders AMERICAN HOME PRODUCTS CORPORATION (US) 1993-08-31 US disclosed
US-5168103-A Neuroprotectants, anticonvulsants AMERICAN HOME PRODUCTS CORPORATION (US) 1992-12-01 US disclosed
EP-0496561-A2 [[(2-Amino-3,4-dioxo-1-cyclobuten-1-yl)amino]alkyl]-acid derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1992-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MUC1, RNMT, FABP2 MEN1 1496/4885GAA 1245/4885KMT2A 2443/4885
US-20020049191-A1 Cephalosporin derivatives MRPL21, CIAPIN1, LTN1 MEN1 1330/4885GAA 2139/4885KMT2A 4106/4885
US-20260109732-A1 LIPID AMINES LDLR, NPC1, PHOSPHO1 MEN1 1812/4885GAA 3145/4885KMT2A 1139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.