Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597620 | 0.81 | ESR1 (0.51) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL8561159 | 0.81 | SMN1; SMN2 (0.42) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL7720682 | 0.80 | TDP1 (0.51) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL8568311 | 0.80 | ALOX15 (0.53) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL8568794 | 0.79 | HPGD (0.54) | ALDH1A1GAAKMT2AMEN1MAPK1 | |
| SCHEMBL6079780 | 0.78 | APP (0.47) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL2906705 | 0.78 | MAPT (0.49) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL8567516 | 0.78 | AGTR1 (0.48) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL8559145 | 0.77 | GRM2 (0.52) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL8567699 | 0.77 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |