Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.37 |
| ▸ | TUBB | P07437 | 5/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558658 | 0.78 | CCNB2 (0.37) | KDM4EALDH1A1GAAKMT2ACCNB2 | |
| SCHEMBL27917762 | 0.76 | PDE4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10833235 | 0.72 | KDM4E (0.36) | HTTKDM4EALDH1A1PDE3BPDE3A | |
| SCHEMBL6883568 | 0.72 | CCNB2 (0.34) | KDM4EPOLBGAAKMT2ACCNB2 | |
| SCHEMBL557929 | 0.71 | KEAP1 (0.44) | ALDH1A1POLBPDE3BPDE3ALMNA | |
| SCHEMBL433019 | 0.70 | CYP3A4 (0.42) | HTTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL3728677 | 0.69 | LTA4H (0.52) | HTTKDM4EALDH1A1POLBGAA | |
| SCHEMBL8566928 | 0.69 | NQO2 (0.30) | — | |
| SCHEMBL8859957 | 0.69 | LTA4H (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8814960 | 0.69 | PARP1 (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821675-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033176-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |