Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833235 | 0.78 | KDM4E (0.36) | NQO2 | |
| SCHEMBL6883568 | 0.78 | CCNB2 (0.34) | NQO2 | |
| SCHEMBL8563838 | 0.77 | SIRT1 (0.30) | — | |
| SCHEMBL557929 | 0.73 | KEAP1 (0.44) | NQO2 | |
| SCHEMBL2955217 | 0.70 | CA2 (0.43) | NQO2 | |
| SCHEMBL8562960 | 0.69 | TUBB4A (0.37) | — | |
| SCHEMBL18894095 | 0.68 | TRPA1 (0.33) | — | |
| SCHEMBL18894114 | 0.67 | — | — | |
| SCHEMBL8566667 | 0.66 | MAPT (0.45) | — | |
| SCHEMBL8564792 | 0.66 | RAC1 (0.42) | NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821675-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033176-A1 | NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |