Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15155567 | 0.80 | CYP3A4 (0.55) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL11409450 | 0.79 | GSTP1 (0.54) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL5376331 | 0.78 | MEN1 (0.65) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL10681839 | 0.76 | MEN1 (0.56) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL8568330 | 0.76 | PIN1 (0.44) | MEN1KMT2ACYP3A4PIN1EGFR | |
| SCHEMBL10263365 | 0.76 | CYP3A4 (0.61) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL11415231 | 0.76 | PDE7A (0.52) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL8561788 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AGSTP1GSTM2CYP1A2 | |
| SCHEMBL23833475 | 0.76 | POLB (0.54) | MEN1KMT2ACYP1A2CYP2C19HPGD | |
| SCHEMBL8595123 | 0.75 | EGFR (0.36) | MEN1KMT2AHPGDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |