Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TPO | P07202 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | EPX | P11678 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24455815 | 0.78 | NOS3 (0.50) | EGFRMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8567785 | 0.77 | PIN1 (0.53) | PIN1CYP19A1CYP11B1CYP11B2MEN1 | |
| SCHEMBL8570918 | 0.76 | ALDH1A1 (0.44) | PIN1EGFRMEN1KMT2ACYP3A4 | |
| SCHEMBL8562996 | 0.76 | MEN1 (0.52) | PIN1EGFRMEN1KMT2ACYP3A4 | |
| SCHEMBL8560894 | 0.76 | HTR6 (0.55) | EGFRMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8568601 | 0.75 | ALDH1A1 (0.56) | PIN1EGFRCYP19A1MEN1KMT2A | |
| SCHEMBL8567165 | 0.75 | PIN1 (0.40) | PIN1EGFRCYP3A4 | |
| SCHEMBL8566589 | 0.74 | PIM3 (0.44) | EGFRMEN1KMT2ANPC1MAPT | |
| SCHEMBL8568534 | 0.73 | CYP19A1 (0.40) | PIN1CYP19A1CYP11B1CYP11B2NPC1 | |
| SCHEMBL8562212 | 0.73 | PIN1 (0.46) | PIN1EGFRCYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |